Diablo 4 Season 6: Season of Hatred Rising - Master All Runes and Runewords

04.10.2024 - 12:28:17
Diablo 4 , Game Guides , Gameplay Guides , Items

Diablo 4 Season 6: Season of Hatred Rising - Master All Runes and Runewords

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Have you played Diablo II or Diablo II Resurrected and thought to yourself if the Rune Word system will ever come back? Well, Blizzard has some good news for you! With the upcoming release of Diablo 4 Season 6: Season of Hatred Rising, Runes and Runewords are back!

Season 6 will launch on October 7 complete with new mechanics, challenges, and the ever-beloved Runes System, similar to the previous installments in the Diablo franchise.

Whether you’re a seasoned Diablo veteran or a new player looking to craft the most powerful builds, this guide will walk you through everything you need to know about Diablo 4 Runes and Runewords and how to master this essential system come Season 6. So without further ado, let’s get started!

Diablo 4 Runes and Runewords: An Overview

Runes, items that grant powerful bonuses that were first introduced in Diablo II, have now returned to Diablo 4 in Season of Hatred Rising. Unlike in the past, however, there are some notable differences in their implementation this time around.

Runes in Diablo 4 are divided into two types—Runes of Ritual and Runes of Invocation. Certain Runes can be combined to form Runewords, which grant better and more powerful effects. This system builds on the legendary mechanics of Diablo II but adds a new layer of complexity with the new Offering System that ties effects to specific in-game actions.

Diablo 4 New Season Runes, Runewords, Items, Services

How the Rune System Works

  • Runes of Ritual: These are the triggers that will grant bonuses via the Runes of Invocation. You will need to do something specific in order to activate the rune. Examples include Bac (Travel 5 Meters) and Zan (Cast an Ultimate Skill).
  • Runes of Invocation: These runes grant bonuses once the trigger requirements of the Runes of Ritual are satisfied. For example, the Vex Rune raises the level of all your skills by three for five seconds.

When combined, these runes form Runewords, which can drastically enhance your build's power. To activate a Runeword’s effects, you must meet the Offering requirement depending on the Rune of Invocation you have chosen.

Full Runes List for Diablo 4 Season 6

Runes of Ritual

RuneOfferingTriggerTips
Moni10 OfferingCast a skill after moving (Cooldown of 0.2 seconds)A good rune to use for highly mobile builds
Cir25 OfferingCast the same non-channeled skill 3 times in a rowAmazing for active skill-intensive builds
Cem50 OfferingCast EvadeA good rune for most D4 builds
Yax100 OfferingDrink a Healing PotionUseful for squishy builds that need a constant use of healing potions to survive
Zan150 OfferingCast an Ultimate SkillGood for most D4 builds
Poc2 OfferingSpend 5% of your Maximum ResourcePerfect for skill-spamming builds
Noc5 OfferingInflict any crowd control effect other than slow or chillChoose this if your build relies on CC
Neo300 OfferingDeal damage after not taking any within five seconds (resets when you are invulnerable)Builds that have impeccable dodge can benefit from this
Feo1000 OfferingBecome injured or crowd-controlled (20-second cooldown)Use this whenever you fight enemies with CC abilities
Ahu10 OfferingUp to a 100% chance against injured enemiesGood for builds that deal burst damage
Lith25 OfferingStand still for 0.3 secondsGreat for most builds
Tam25 OfferingCast a non-channeled Core SkillIncredible for builds that do not rely on channeled abilities
Yul50 OfferingCast a skill with a cooldownGood for most builds
Bac50 OfferingTravel 5 metersGood for builds, even more so for highly mobile ones
Xol150 OfferingEvoke power from another classGood for most builds

Runes of Invocation

RuneOfferingCool DownPowerOverflowTips
Lum5 Offering1 secRestore 1 Primary ResourceGain multiple stacksGood for builds that rely on spamming skills
Ton25 Offering1 secEvoke the Sorcerer’s Meteorites dealing damage to enemiesIncreased Meteorites spawnedGreat for high magic builds
Gar25 Offering1 secGain 2.5% critical strike chance for 5 seconds up to 25%Gain multiple stacksBest for builds that have a relatively high critical strike chance
Met100 Offering1 secYou leave the Necromancer’s Desecrated Ground behind you for 3 seconds dealing damage to enemies withinIncreased durationGood for builds that utilize AoE abilities
Tal100 Offering1 secEvoke the Spiritborn’s Pestilent Swarm dealing damage to enemiesIncreased Swarms spawnedGood for clearing crowds
Teb100 Offering1 secEvoke the Necromancer’s Abhorrent Iron Maiden counterattacking damage from enemies and healing you when they dieNoneGreat for survivability
Tec100 Offering1 secEvoke the Barbarian’s Earthquake ability dealing damage to enemies withinIncreased SizeAmazing when your build relies on AoE abilities
Tun100 Offering1 secEvoke the Rogue’s Stun Grenades stunning and dealing damage to enemiesIncreased Grenades spawnedGood for dealing with high-damage monsters
Wat100 Offering1 secEvoke the Necromancer’s Horrid Decrepify slowing enemies down, reducing their damage, and letting you “Execute” themNoneAmazing for any build
Mot150 Offering1 secGain a shadow from the Rogue’s Dark Shroud reducing damage taken per shadowGain multiple ShadowsGreat for builds that have low survivability
Zec200 Offering2 secsReduce your active Ultimate cooldown by 4 secondsFurther reduced cooldownUse if you rely heavily on your character’s ultimate ability
Xal200 Offering1 secGain 20% maximum life for 4 secondsIncreased DurationGood for squishy builds
Tzic250 Offering1 secEvoke the Spiritborn’s Concussive Stomp ability dealing damage and knocking enemies downNoneIncredible for dealing with large packs of monsters
Thul400 Offering1 secEvoke the Sorcerer’s Mystical Frost Nova inflicting Freeze and Vulnerable onto enemiesIncreased AoEAmazing for clearing big groups of monsters
Qua400 Offering1 secRestore an Evade charge and gain 6% movement speed for 5 seconds up to 30%Increased durationGood for most builds even more so for Rogues
Qax400 Offering1 secYour next non-Basic Skill cast spends all of your Primary Resource to deal up to 100% increased damageFurther increased damageGreat for builds that utilize Core Skills frequently
Kry500 Offering3 secsEvoke the Spiritborn’s Vortex dealing damage and pulling enemies inNoneIncredible for HotA Barbs and builds that use AoE to kill enemies
Ner700 Offering6 secsEvoke the Rogue’s Countering Concealment ability gaining increased dodge chance, movement speed, Unstoppable, and StealthIncreased DurationGreat for squishy yet highly mobile builds
Lac800 Offering1 secEvoke the Barbarian’s Challenging Shout reducing your damage takenIncreased durationGood for builds with low survivability
Que800 Offering1 secEvoke the Druid’s Earthen Bulwark granting yourself a BarrierIncreased durationGood for all builds, especially squishy ones
Eom100 Offering1 secReduce your active cooldowns by 0.25 secondsFurther reduced cooldownsVery useful for builds that rely on abilities with cooldowns
Vex400 Offering1 secGain +3 to all Skills for 5 secondsIncreased durationAmazing for all builds
Yom500 Offering5 secsEvoke the Druid’s Petrify stunning enemies and increasing your critical strike damage against themNoneGreat for crit-based builds
Jah500 Offering2 secsReplace your next Evade with the Sorcerer’s Teleport, blinking further, dealing damage, and becoming “Unstoppable”NoneAmazing for all builds, particularly the squishy ones
Ohm500 Offering2 secsEvoke the Barbarian’s Enhanced War Cry increasing your movement speed and damage dealtIncreased durationGood for all builds
Xan700 Offering1 secYour next Skill cast will be a guaranteed critical strike and OverpowerNoneGood for all builds, especially those with low critical strike chance

How to Get Runes in Diablo 4 Season 6

D4_Runes_Season_6

Now that you know what the runes do, how exactly do you get your hands on them?

  • Tormented Bosses: Some of the best chances to acquire runes are from Tormented Bosses, which are high-level enemies that can only be summoned on World Tier 4: Torment.
  • World Events and Rune Caches: Participating in world events can reward you with Rune Caches.
  • Trading: Runes are fully tradeable, so keep an eye out for trading opportunities if you’re short on a particular rune for your ideal Rune Word combination.
  • Runecrafting: You can combine three of the same runes to create a random rune. It is possible to gain a rune of higher rarity via Runecrafting.

How to Create and Use Runewords

Once you’ve gathered your Runes, crafting a Runeword is the next step. Here’s how to do it:

  1. Check Your Gear: Make sure that your chosen item has two sockets as runewords require exactly two runes—one Ritual Rune and one Invocation Rune.
  2. Combine Runes: Place one Ritual Rune and one Invocation Rune into your item’s sockets to form a runeword.
  3. Meet Offering Requirements: To activate the runeword’s effect, you must meet its Offering condition, such as using a cooldown ability, dealing critical damage, or evading an attack.

Best Runewords for Diablo 4 Classes in Season 6

ClassBest Runeword StrategyRecommended Runes
BarbarianBoost raw damage and survivabilityMoni + Qax
SorcererMaximize cooldown reductionYul + Zec
RogueIncrease burst damage and mobilityCem + Gar
DruidEnhance shapeshifting and sustainUr + Lac
NecromancerAmplify summon damage and survivabilityUr + Wat

Expert Tips on How to Unlock the Runes’ Full Potential

  • Don’t Be Afraid to Experiment: There are a total of 45 runes in Patch 2.0, so find the combination that works best for your build.
  • Take Advantage of Offerings: Remember that you only get bonuses when you get enough Offerings. Make sure that the Rune of Ritual and Rune of Invocation you use complement your playstyle.
  • Utilize Unsocketing: Unlike Diablo II where socketing was permanent, Diablo 4 allows you to remove runes from your items without destroying them, giving you the freedom to experiment with various combinations and fine-tune your gear!
  • Use Runes to Get Highly Coveted Items: You can use runes to craft Mythic Unique items. Some of these items include the Harlequin Crest and Tyrael’s Might! Check out the table below:
ItemRunesEffects
Harlequin Crest10x Eom Rune
10x Lac Rune
10x Ton Rune
20% Cooldown Reduction
+1850 Maximum Life
+18 Maximum Resistance
+2500 Armor
Gain 20% Damage Reduction
+4 Ranks to All Skills
Tyrael’s Might10x Lith Rune
10x Feo Rune
10x Met Rune
20% Damage Reduction
+16.5% Movement Speed
+60% Resistance to All Elements
+7.5% Maximum Resistance to All Elements
While at full life your skills unleash a divine barrage dealing 1% weapon damage to nearby enemies
The Grandfather10x Xol Rune
10x Kaa Rune
10x Yax Rune
+75 to All Stats
+150% Damage
+1679 Maximum Life
+10 Maximum Resource
Increases your critical strike damage by 100%
Doombringer10x Ahu Rune
10x Neo Rune
10x Lum Rune
+114 to All Stats
10% Damage Reduction
35% Maximum Life
Lucky Hit: Up to a 25% chance to deal 6% of weapon damage as shadow damage to surrounding enemies and reduce their damage dealt by 20% for 5 seconds
Lucky Hit: Up to a 5% Chance to Heal +2687 Life
Melted Heart of Selig10x Vex Rune
10x Thul Rune
10x Tun Rune
15% Damage Reduction while Healthy
+15% Lucky Hit Chance
+25% Movement Speed
15% Resource Generation
Gain 60 Maximum Resource
When taking damage, 75% is drained as 2 Resource for every 1% of Maximum Life you would have lost
Ring of Starless Skies10x Ohm Rune
10x Tzic Rune
10x Cem Rune
+17.5% Attack Speed
+12.5% Critical Strike Chance
+12.5% Lucky Hit Chance
+2 to Core Skills
Spending your Primary Resource reduces the resource cost of your skills and increases your damage by 10% for 3 seconds up to 50%
Andariel’s Visage10x Tam Rune
10x Qax Rune
10x Zan Rune
+30% Attack Speed
+77 to All Stats
+437 Life on Hit
+10% Maximum Resistance
Lucky Hit: Up to a 20% chance to trigger a poison nova that applies 30% of weapon damage as poisoning damage over 5 seconds to enemies in the area
Ahavarion Spear of Lycander10x Yom Rune
10x Poc Rune
10x Cir Rune
+9% to All Stats
+16.5% Movement Speed
+33% Resistance to All Elements
Gain a random Shrine effect for 20 seconds after killing an Elite enemy. Can only occur once every 30 seconds
Lucky Hit: Up to a 5% Chance to Restore +33% Primary Resource
Heir of Perdition10x Jah Rune
10x Que Rune
10x Gar Rune
+200% Damage to angels and demons
+20% Critical Strike Chance
+20% Lucky Hit Chance
20% Movement Speed
+2 to Core Skills
Shroud of False Death10x Bac Rune
10x Kry Rune
10x Ur Rune
+111 to All Stats
+333% Damage on next attack after entering Stealth
+222 Maximum Life
11.1% Resource Generation
If you haven’t attacked in the last 2 seconds, gain Stealth and 40% movement speed
Shattered Vow10x Xan Rune
10x Ner Rune
10x Teb Rune
+29.6% Attack Speed while Berserking
+444.4% Damage over time
+444 Maximum Life
Lucky Hit: Up to a +44.4% chance to become Berserking
Execute enemies afflicted by more damage over time than remaining life

Unleash Your Full Potential in the Vessel of Hatred Expansion

As Season 6: Season of Hatred Rising introduces new mechanics and the highly anticipated Vessel of Hatred expansion, there’s never been a better time to develop your strategies and experiment with what works best for you. From new zones and bosses to crafting unbeatable runewords, the massive changes that are coming to the game will truly shake things up. Are you ready to vanquish the forces of Mephisto on October 7?

Season and Expansion Release Dates & Times

Diablo 4 Season 6: Season of Hatred Rising and the Vessel of Hatred expansion will launch on October 7, 2024, at 16:00 PDT across all platforms—PC, PlayStation, and Xbox. The global release times by region are as follows:

  • North America: 07 October 2024 16:00 PDT (4 PM), 07 October 2024 19:00 EDT (7 PM)
  • Europe: 08 October 2024 00:00 BST (12 MN), 08 October 2024 01:00 CEST (1 AM)
  • Asia: 08 October 2024 08:00 KST (8 AM), 08 October 2024 09:00 AEST (9 AM)
Buy the Best Diablo 4 Runes, Items and Services

Want to get your hands on the best possible gear early on in Season 6?

Visit RPGStash Diablo 4 Store for the best runes, gear, and services to get ahead and dominate the Season of Hatred Rising!

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